2024 Trend Updates: What Really Works In SEO & Content MarketingSearch Engine Journal
The future of SEO is trending toward a more human-first and user-centric approach, powered by AI intelligence and collaboration. Are you ready?
Watch as we explore which SEO trends to prioritize to achieve sustainable growth and deliver reliable results. We’ll dive into best practices to adapt your strategy around industry-wide disruptions like SGE, how to navigate the top challenges SEO professionals are facing, and proven tactics for prioritizing quality and building trust.
You’ll hear:
- The top SEO trends to prioritize in 2024 to achieve long-term success.
- Predictions for SGE’s impact, and how to adapt.
- What E-E-A-T really means, and how to implement it holistically (hint: it’s never been more important).
With Zack Kadish and Alex Carchietta, we’ll show you which SEO trends to ignore and which to focus on, along with the solution to overcoming rapid, significant and disruptive Google algorithm updates.
If you’re looking to cut through the noise of constant SEO and content trends to drive success, you won’t want to miss this webinar.
Storytelling For The Web: Integrate Storytelling in your Design ProcessChiara Aliotta
In this slides I explain how I have used storytelling techniques to elevate websites and brands and create memorable user experiences. You can discover practical tips as I showcase the elements of good storytelling and its applied to some examples of diverse brands/projects..
This presentation by Thibault Schrepel, Associate Professor of Law at Vrije Universiteit Amsterdam University, was made during the discussion “Artificial Intelligence, Data and Competition” held at the 143rd meeting of the OECD Competition Committee on 12 June 2024. More papers and presentations on the topic can be found at oe.cd/aicomp.
This presentation was uploaded with the author’s consent.
How to Leverage AI to Boost Employee Wellness - Lydia Di Francesco - SocialHR...SocialHRCamp
Speaker: Lydia Di Francesco
In this workshop, participants will delve into the realm of AI and its profound potential to revolutionize employee wellness initiatives. From stress management to fostering work-life harmony, AI offers a myriad of innovative tools and strategies that can significantly enhance the wellbeing of employees in any organization. Attendees will learn how to effectively leverage AI technologies to cultivate a healthier, happier, and more productive workforce. Whether it's utilizing AI-powered chatbots for mental health support, implementing data analytics to identify internal, systemic risk factors, or deploying personalized wellness apps, this workshop will equip participants with actionable insights and best practices to harness the power of AI for boosting employee wellness. Join us and discover how AI can be a strategic partner towards a culture of wellbeing and resilience in the workplace.
2024 State of Marketing Report – by HubspotMarius Sescu
https://www.hubspot.com/state-of-marketing
· Scaling relationships and proving ROI
· Social media is the place for search, sales, and service
· Authentic influencer partnerships fuel brand growth
· The strongest connections happen via call, click, chat, and camera.
· Time saved with AI leads to more creative work
· Seeking: A single source of truth
· TLDR; Get on social, try AI, and align your systems.
· More human marketing, powered by robots
ChatGPT is a revolutionary addition to the world since its introduction in 2022. A big shift in the sector of information gathering and processing happened because of this chatbot. What is the story of ChatGPT? How is the bot responding to prompts and generating contents? Swipe through these slides prepared by Expeed Software, a web development company regarding the development and technical intricacies of ChatGPT!
Product Design Trends in 2024 | Teenage EngineeringsPixeldarts
The realm of product design is a constantly changing environment where technology and style intersect. Every year introduces fresh challenges and exciting trends that mold the future of this captivating art form. In this piece, we delve into the significant trends set to influence the look and functionality of product design in the year 2024.
How Race, Age and Gender Shape Attitudes Towards Mental HealthThinkNow
Mental health has been in the news quite a bit lately. Dozens of U.S. states are currently suing Meta for contributing to the youth mental health crisis by inserting addictive features into their products, while the U.S. Surgeon General is touring the nation to bring awareness to the growing epidemic of loneliness and isolation. The country has endured periods of low national morale, such as in the 1970s when high inflation and the energy crisis worsened public sentiment following the Vietnam War. The current mood, however, feels different. Gallup recently reported that national mental health is at an all-time low, with few bright spots to lift spirits.
To better understand how Americans are feeling and their attitudes towards mental health in general, ThinkNow conducted a nationally representative quantitative survey of 1,500 respondents and found some interesting differences among ethnic, age and gender groups.
Technology
For example, 52% agree that technology and social media have a negative impact on mental health, but when broken out by race, 61% of Whites felt technology had a negative effect, and only 48% of Hispanics thought it did.
While technology has helped us keep in touch with friends and family in faraway places, it appears to have degraded our ability to connect in person. Staying connected online is a double-edged sword since the same news feed that brings us pictures of the grandkids and fluffy kittens also feeds us news about the wars in Israel and Ukraine, the dysfunction in Washington, the latest mass shooting and the climate crisis.
Hispanics may have a built-in defense against the isolation technology breeds, owing to their large, multigenerational households, strong social support systems, and tendency to use social media to stay connected with relatives abroad.
Age and Gender
When asked how individuals rate their mental health, men rate it higher than women by 11 percentage points, and Baby Boomers rank it highest at 83%, saying it’s good or excellent vs. 57% of Gen Z saying the same.
Gen Z spends the most amount of time on social media, so the notion that social media negatively affects mental health appears to be correlated. Unfortunately, Gen Z is also the generation that’s least comfortable discussing mental health concerns with healthcare professionals. Only 40% of them state they’re comfortable discussing their issues with a professional compared to 60% of Millennials and 65% of Boomers.
Race Affects Attitudes
As seen in previous research conducted by ThinkNow, Asian Americans lag other groups when it comes to awareness of mental health issues. Twenty-four percent of Asian Americans believe that having a mental health issue is a sign of weakness compared to the 16% average for all groups. Asians are also considerably less likely to be aware of mental health services in their communities (42% vs. 55%) and most likely to seek out information on social media (51% vs. 35%).
🔬 Introduction: Understanding Type IV Hypersensitivity
Type IV hypersensitivity is a delayed-type hypersensitivity (DTH), unlike immediate hypersensitivity reactions (Types I-III). 🕒
It is T-cell mediated rather than antibody-driven. This means it involves CD4+ T helper cells (Th1, Th17) and CD8+ cytotoxic T cells rather than IgE, IgG, or IgM. 🦠
The response takes 24-72 hours after exposure to an antigen, which is why it is called delayed. ⏳
Examples include contact dermatitis, tuberculosis (TB) skin reactions, granulomatous inflammation, and transplant rejection. 🏥
---
🧬 Pathophysiology: How It Works?
1. Sensitization Phase (First Exposure) 🏗️
The antigen (e.g., nickel, TB antigen, or poison ivy urushiol) is processed by antigen-presenting cells (APCs) like macrophages and dendritic cells.
These APCs present the antigen on MHC-II molecules to naïve CD4+ T cells, activating them. ⚡
CD4+ T cells differentiate into Th1 (mainly) and Th17 cells, producing cytokines like IFN-γ and TNF-α.
2. Effector Phase (Second Exposure) 🎯
Upon re-exposure, memory Th1 cells release cytokines (IFN-γ, TNF-α, IL-2), activating macrophages. 🔥
Macrophages become hyperactivated, releasing enzymes, reactive oxygen species (ROS), and inflammatory mediators, leading to tissue destruction. 💣
In some cases, CD8+ T cells also get activated and kill infected or abnormal cells directly. 🗡️
---
📌 Types of Type IV Hypersensitivity Reactions
There are four major subtypes based on mechanisms and clinical presentations:
1️⃣ Contact Hypersensitivity (Eczema & Contact Dermatitis) 🤲🔴
Triggers: Poison ivy, nickel, latex, fragrances, hair dye. 🌿💍🧤
Mechanism: Small molecules (haptens) bind to skin proteins → APCs present them → Th1 cells activate macrophages → local inflammation and rash.
Example: Poison ivy reaction (blisters, redness, itching).
2️⃣ Tuberculin-Type Hypersensitivity (Mantoux Test) 💉🦠
Triggers: Mycobacterium tuberculosis, Histoplasma, Brucella.
Mechanism: Injected PPD (Purified Protein Derivative) activates memory Th1 cells → Macrophages release cytokines → Local induration and erythema within 48-72 hours.
Example: Mantoux (PPD) Test for tuberculosis.
3️⃣ Granulomatous Hypersensitivity (Chronic Inflammation) 🦠⏳
Triggers: TB, Leprosy, Sarcoidosis, Crohn’s disease, Schistosomiasis.
Mechanism: Persistent antigenic stimulation → Th1 cells release IFN-γ → Macrophages transform into epithelioid cells and multinucleated giant cells → Granuloma formation (walling off infection).
Example: TB granuloma with caseous necrosis.
4️⃣ T-cell Mediated Cytotoxicity (Graft Rejection & Autoimmunity) 🏥⚔️
Triggers: Organ transplants, viral infections, Type 1 Diabetes, Hashimoto’s thyroiditis.
Mechanism: CD8+ T cells recognize infected or foreign cells and kill them via perforins and granzymes.
Good Laboratory Practices (GLP) Ensuring Quality and Compliance.pptxDr. Smita Kumbhar
Good Laboratory Practices (GLP): Ensuring Quality and Compliance
Good Laboratory Practices (GLP) is a set of principles intended to ensure the quality, integrity, and reliability of non-clinical laboratory studies that support research and regulatory submissions. These guidelines are critical in the pharmaceutical, biotechnological, chemical, and environmental sectors, ensuring that laboratory-generated data are reproducible, credible, and internationally accepted.
GLP standards primarily apply to safety studies involving pharmaceuticals, pesticides, food additives, and industrial chemicals. Regulatory agencies, including the USFDA, EMA, and OECD, enforce GLP compliance to maintain scientific rigor and public safety.
USFDA GLP Regulations The U.S. Food and Drug Administration (USFDA) established Good Laboratory Practice regulations under 21 CFR Part 58. These regulations outline responsibilities for study directors, testing facilities, and personnel to maintain quality and integrity in non-clinical laboratory studies. The regulations cover various aspects, including study conduct, reporting, and archiving, ensuring consistency and accuracy in laboratory research.
Controlling the GLP Inspection Process
Regulatory authorities conduct inspections to verify GLP compliance. Laboratories must prepare for inspections by:
• Maintaining up-to-date documentation.
• Conducting internal audits.
• Ensuring personnel training and awareness.
• Implementing corrective actions for non-compliance.
Regulatory inspections typically assess laboratory infrastructure, personnel competence, study documentation, and adherence to protocols. Laboratories must demonstrate transparency and proactive quality control measures.
Documentation in GLP
Accurate and comprehensive documentation is crucial in GLP compliance. Key documentation elements include:
• Study protocols
• Standard operating procedures (SOPs)
• Raw data records
• Analytical reports
• Audit reports
• Equipment calibration records
• Archiving and retention policies
Proper documentation ensures traceability, accountability, and reliability in laboratory research.
Audit in GLP Compliance
Auditing is a critical component of GLP, ensuring adherence to established regulations and identifying areas for improvement. Audits can be internal (self-audit) or external (regulatory or third-party audits).
Goals of Laboratory Quality Audit
• Ensure compliance with GLP regulations.
• Identify gaps and areas for improvement.
• Validate data integrity and accuracy.
• Enhance operational efficiency.
• Prevent regulatory penalties and study disqualification.
Audit Tools in GLP
Laboratories use various audit tools to assess compliance, including:
• Checklists and self-assessments
• Internal quality audits
• Electronic data tracking systems
• Third-party inspections
• Root cause analysis
• Corrective and preventive action (CAPA) plans
Future of GLP Regulations
Learning Objectives:
1. Explain the basis of Nernst potential and its importance in generation of resting membrane potential
2. Comprehend different mechanisms responsible for the genesis of membrane potential
3. Use the Goldman equation to explain how the relative permeability of the ions create a resting membrane potential
Co-Chairs and Presenters, Professor Carel le Roux, MBChB, FRCP, FRCPath, PhD, and Donna H. Ryan, MD, FTOS, discuss obesity in this CME activity titled “Adopting Modern Management Strategies for Obesity: Treating the Patient, Not the Disease.” For the full presentation, downloadable Practice Aids, and complete CME information, and to apply for credit, please visit us at https://bit.ly/40HfQWa. CME credit will be available until March 27, 2026.
### **Acyclovir and Anti-Herpes Medications**
**Acyclovir** is an antiviral medication used to treat infections caused by herpes viruses, including:
- **Herpes simplex virus (HSV-1 & HSV-2)** – Causes cold sores and genital herpes.
- **Varicella-zoster virus (VZV)** – Causes chickenpox and shingles.
### **Mechanism of Action:**
Acyclovir works by inhibiting viral DNA replication. It is activated inside virus-infected cells, where it blocks viral enzymes, preventing the virus from multiplying.
### **Forms & Dosage:**
- **Oral (Tablets/Capsules/Liquid)** – Used for mild to moderate infections.
- **Topical (Cream/Ointment)** – For cold sores and mild skin infections.
- **Intravenous (IV)** – For severe infections like herpes encephalitis.
### **Other Anti-Herpes Medications:**
- **Valacyclovir (Valtrex)** – A prodrug of acyclovir with better absorption.
- **Famciclovir (Famvir)** – Another antiviral with a longer duration of action.
- **Penciclovir (Denavir)** – Used topically for herpes labialis (cold sores).
### **Uses:**
- Treats and manages outbreaks of herpes simplex.
- Reduces the severity and duration of symptoms.
- Used for long-term suppression to prevent recurrent infections.
- Helps in managing shingles and chickenpox.
### **Side Effects:**
- Nausea, vomiting, diarrhea.
- Headache, dizziness, fatigue.
- Rare: Kidney issues, allergic reactions.
### **Precautions:**
- Drink plenty of fluids to prevent kidney issues.
- Not a cure, but helps manage symptoms.
- Safe for most patients but should be used cautiously in people with kidney disease or weakened immune systems.
Plasma and Red Blood Cells - Copy - Copy_AntiCopy.pdfMedicoseAcademics
Delve deep into the intricate world of blood physiology with “Plasma and Red Blood Cells,” a comprehensive lecture presented by Dr. Faiza, Assistant Professor of Physiology. This presentation is meticulously designed for students, educators, and healthcare professionals to enhance their understanding of hematology and the critical roles played by various blood components.
In this lecture, you will:
Examine Blood Composition:
Learn how blood constitutes approximately 8% of total body weight, with precise volumes differing between genders. The presentation breaks down blood into its two fundamental components—plasma and blood cells—and explains their distribution and essential functions in the body.
Understand Plasma Functions and Composition:
Discover the key role of plasma as a transport medium for nutrients, waste products, hormones, and ions. The lecture details the high water content (~90%), the balance of inorganic (e.g., Na⁺, Cl⁻, HCO₃⁻, K⁺, Ca²⁺) and organic substances (notably plasma proteins), and how these components contribute to maintaining homeostasis, temperature regulation, and pH balance.
Classify Plasma Proteins:
Explore the classification of plasma proteins into albumins, globulins (alpha, beta, and gamma), and fibrinogen. Learn about their individual functions, such as maintaining colloid osmotic pressure, facilitating transport of poorly soluble substances, and contributing to immune defense and clotting processes.
Analyze Hematocrit and Packed Cell Volume (PCV):
Understand the significance of hematocrit or PCV as a measure of the proportion of erythrocytes in blood, including the average values observed in men and women. This metric is crucial for assessing blood viscosity and overall health.
Study the Structure and Function of Erythrocytes:
Gain insight into the unique characteristics of red blood cells, including their biconcave disc shape, deformability, and the absence of organelles, which all play a role in optimizing oxygen transport. Detailed discussions cover the enzymes involved in RBC metabolism and the physiological basis for their limited lifespan.
Relate to Clinical and Physiological Contexts:
The lecture also connects these fundamental concepts to clinical scenarios, explaining how alterations in blood composition can impact oxygen delivery, acid-base balance, and overall metabolic function. It provides a solid foundation for understanding common hematological disorders and the body’s adaptive mechanisms in various pathological conditions.
Each slide is carefully structured to build a comprehensive picture of blood components and their interplay, supported by visual aids such as flow diagrams, comparative charts, and schematic representations. Dr. Faiza’s expertise is evident as she translates complex physiological processes into accessible and practical knowledge, making this presentation a valuable resource for enhancing your medical education.
CROUP.pdf FOR NURSING STUDENTS CREATED BY KIRAN KARETHAKIRAN KARETHA
Croup is a common childhood illness characterized by swelling
in the airway (larynx, Trachea and bronchi), leading to a
distinctive barking cough and difficulty in breathing, often with
a high-pitched, noisy sound called stridor when inhaling.
It is also known as laryngotracheobronchitis.
THE WESTLEY SCORE: classification of croup severity
SCORING SYSTEM:
A total score of < 2 indicates mild croup.
A total score of 3-5 is classifies as moderate croup.
A total score of 6-11 indicates severe croup.
A total score of >12 indicates impending respiratory failure.
The score ranges from 0-17.
MANAGEMENT:
Supportive care including intravenous fluids to maintain hydration
and oxygen inhalation to relieve hypoxia has to be given.
A single dose of dexamethasone 0.6mg/kg may decrease severity
and duration of illness.
Inhalation of epinephrine may decrease the symptoms of stridor and
respiratory distress immediately.
PREVENTION:
Many cases of croup have been prevented by immunization for
influenza and diphtheria.
Learning Objectives:
1. Discuss free water clearance
2. Differentiate between diabetes insipidus and SIADH
3. Describe the control of extracellular fluid osmolarity and sodium concentration in terms of the osmoreceptor-ADH system and thirst mechanism
4. Describe the roles of Angiotensin II, Aldosterone, and salt appetite mechanism in the control of extracellular fluid osmolarity and sodium concentration
Yasser’s Electrocardiographic Palpitations Wave with Bilobed Apical Floating ...YasserMohammedHassan1
Bilobed Apex heart with Floating Heart syndrome is an innovative cardiovascular and radiological discovery. The Bilobed Apex heart with Floating Heart syndrome with "Yasser’s Electrocardiographic Palpitations Waves" and off-phenomenon post-amiodarone IVB injection are remarkable innovative constellations. "Yasser’s Electrocardiographic Palpitations Waves" was shortly described as a superficial upright wave associated with unusual palpitations. Bilobed Apex heart with Floating Heart has no known cause. It is mostly congenital. The senses of sudden heart stoppage, generalized fatigue, vertigo, acute confusion, generalized body relaxation, a sense of separation from the environment, and a sense of no abnormality within minutes of amiodarone IVB injection are an off phenomenon.
Artificial Intelligence in Medical Studies.pptxMahnoor Fatima
This presentation explores the integration of Artificial Intelligence (AI) in medical studies, focusing on its benefits, challenges, and ethical considerations. As AI continues to shape modern healthcare, understanding students’ perspectives is crucial in designing future medical education programs.
Growth and development milestone 7 months .pptxAbhishek Verma
Growth and developed milestone for a 7 months old children
Milestone 7 months
At seven months, your baby is becoming more active, curious, and expressive! Many can sit up without support, reach for toys, and even start rocking on their hands and knees, a sign that crawling is coming soon. Their grip is improving, so they enjoy grabbing, shaking, and banging objects together.
Socially, they recognize their name, respond to familiar voices, and may show separation anxiety when a parent leaves the room. They love interactive games like peekaboo and enjoy babbling sounds like “ba-ba” and “da-da.”
Solid foods are now a regular part of their diet, along with breast milk or formula. They may sleep 12–16 hours a day, including two or three naps.
Every baby develops at their own pace, so don’t worry if they’re not hitting every milestone at the same time as others. Enjoy this exciting stage of discovery and growth.
Discover the essential growth and development milestones of a 7-month-old baby. Learn about physical, cognitive, emotional, and social developments, including motor skills, sensory awareness, speech progress, and feeding habits. Get expert parenting tips, activities, and guidance to support your baby's healthy development. Stay informed with this comprehensive guide
Wondering what milestones your 7-month-old should be reaching? This expert guide covers key physical, cognitive, and social developments, from sitting up and babbling to improved
hand-eye coordination. Learn about feeding,
sleep patterns, and fun activities to support your baby's growth. Get top parenting tips and insights to ensure your little one thrives!
#pediatricnursing #Growthanddevelopment
#Growthanddevelopmentalmilestones
Growth and development ppt
Growth and development milestone slideshare ppt
"Comprehensive Medical Guide - Health & Medicine Insights (v10.a5.01)"Victoria855690
"This document provides valuable insights into health and medicine, covering essential topics such as medical research, healthcare practices, disease management, and treatment approaches. It is useful for students, professionals, and researchers in the medical field. The content is well-structured, making complex medical concepts easier to understand."
Prescribing for Heart Failure: A Guide for MBBS StudentsShivankan Kakkar
This SlideShare presentation provides a concise reference for MBBS students on prescription writing for heart failure. It covers key medications, treatment approaches, and clinical guidelines for effective management.
Approach to anemia , classification, investigations casesFatimahRaad
Pdf simply about how to reach to anemia diagnosis with presenting signs and symptoms mainly based on investigations we send in this file as well as discuss two case scenarios on this common health problem from reference book core clinical cases medicine and medical specialties
TRACHEOESOPHAGEAL FISTULA.pdf FOR NURSING STUDENTSKIRAN KARETHA
Tracheoesophageal fistula is an abnormal connection between the
trachea and esophagus.
It occurs in 1 in 3,500 births
Type A (esophageal atresia)
Type B (esophageal atresia with proximal fistula)
Type C (esophageal atresia with Distal fistula)
Type D (esophageal atresia with proximal and distal fistula)
Type E (H- typed fistula)
AI Trends in Creative Operations 2024 by Artwork Flow.pdfmarketingartwork
Creative operations teams expect increased AI use in 2024. Currently, over half of tasks are not AI-enabled, but this is expected to decrease in the coming year. ChatGPT is the most popular AI tool currently. Business leaders are more actively exploring AI benefits than individual contributors. Most respondents do not believe AI will impact workforce size in 2024. However, some inhibitions still exist around AI accuracy and lack of understanding. Creatives primarily want to use AI to save time on mundane tasks and boost productivity.
Organizational culture includes values, norms, systems, symbols, language, assumptions, beliefs, and habits that influence employee behaviors and how people interpret those behaviors. It is important because culture can help or hinder a company's success. Some key aspects of Netflix's culture that help it achieve results include hiring smartly so every position has stars, focusing on attitude over just aptitude, and having a strict policy against peacocks, whiners, and jerks.
🔬 Introduction: Understanding Type IV Hypersensitivity
Type IV hypersensitivity is a delayed-type hypersensitivity (DTH), unlike immediate hypersensitivity reactions (Types I-III). 🕒
It is T-cell mediated rather than antibody-driven. This means it involves CD4+ T helper cells (Th1, Th17) and CD8+ cytotoxic T cells rather than IgE, IgG, or IgM. 🦠
The response takes 24-72 hours after exposure to an antigen, which is why it is called delayed. ⏳
Examples include contact dermatitis, tuberculosis (TB) skin reactions, granulomatous inflammation, and transplant rejection. 🏥
---
🧬 Pathophysiology: How It Works?
1. Sensitization Phase (First Exposure) 🏗️
The antigen (e.g., nickel, TB antigen, or poison ivy urushiol) is processed by antigen-presenting cells (APCs) like macrophages and dendritic cells.
These APCs present the antigen on MHC-II molecules to naïve CD4+ T cells, activating them. ⚡
CD4+ T cells differentiate into Th1 (mainly) and Th17 cells, producing cytokines like IFN-γ and TNF-α.
2. Effector Phase (Second Exposure) 🎯
Upon re-exposure, memory Th1 cells release cytokines (IFN-γ, TNF-α, IL-2), activating macrophages. 🔥
Macrophages become hyperactivated, releasing enzymes, reactive oxygen species (ROS), and inflammatory mediators, leading to tissue destruction. 💣
In some cases, CD8+ T cells also get activated and kill infected or abnormal cells directly. 🗡️
---
📌 Types of Type IV Hypersensitivity Reactions
There are four major subtypes based on mechanisms and clinical presentations:
1️⃣ Contact Hypersensitivity (Eczema & Contact Dermatitis) 🤲🔴
Triggers: Poison ivy, nickel, latex, fragrances, hair dye. 🌿💍🧤
Mechanism: Small molecules (haptens) bind to skin proteins → APCs present them → Th1 cells activate macrophages → local inflammation and rash.
Example: Poison ivy reaction (blisters, redness, itching).
2️⃣ Tuberculin-Type Hypersensitivity (Mantoux Test) 💉🦠
Triggers: Mycobacterium tuberculosis, Histoplasma, Brucella.
Mechanism: Injected PPD (Purified Protein Derivative) activates memory Th1 cells → Macrophages release cytokines → Local induration and erythema within 48-72 hours.
Example: Mantoux (PPD) Test for tuberculosis.
3️⃣ Granulomatous Hypersensitivity (Chronic Inflammation) 🦠⏳
Triggers: TB, Leprosy, Sarcoidosis, Crohn’s disease, Schistosomiasis.
Mechanism: Persistent antigenic stimulation → Th1 cells release IFN-γ → Macrophages transform into epithelioid cells and multinucleated giant cells → Granuloma formation (walling off infection).
Example: TB granuloma with caseous necrosis.
4️⃣ T-cell Mediated Cytotoxicity (Graft Rejection & Autoimmunity) 🏥⚔️
Triggers: Organ transplants, viral infections, Type 1 Diabetes, Hashimoto’s thyroiditis.
Mechanism: CD8+ T cells recognize infected or foreign cells and kill them via perforins and granzymes.
Good Laboratory Practices (GLP) Ensuring Quality and Compliance.pptxDr. Smita Kumbhar
Good Laboratory Practices (GLP): Ensuring Quality and Compliance
Good Laboratory Practices (GLP) is a set of principles intended to ensure the quality, integrity, and reliability of non-clinical laboratory studies that support research and regulatory submissions. These guidelines are critical in the pharmaceutical, biotechnological, chemical, and environmental sectors, ensuring that laboratory-generated data are reproducible, credible, and internationally accepted.
GLP standards primarily apply to safety studies involving pharmaceuticals, pesticides, food additives, and industrial chemicals. Regulatory agencies, including the USFDA, EMA, and OECD, enforce GLP compliance to maintain scientific rigor and public safety.
USFDA GLP Regulations The U.S. Food and Drug Administration (USFDA) established Good Laboratory Practice regulations under 21 CFR Part 58. These regulations outline responsibilities for study directors, testing facilities, and personnel to maintain quality and integrity in non-clinical laboratory studies. The regulations cover various aspects, including study conduct, reporting, and archiving, ensuring consistency and accuracy in laboratory research.
Controlling the GLP Inspection Process
Regulatory authorities conduct inspections to verify GLP compliance. Laboratories must prepare for inspections by:
• Maintaining up-to-date documentation.
• Conducting internal audits.
• Ensuring personnel training and awareness.
• Implementing corrective actions for non-compliance.
Regulatory inspections typically assess laboratory infrastructure, personnel competence, study documentation, and adherence to protocols. Laboratories must demonstrate transparency and proactive quality control measures.
Documentation in GLP
Accurate and comprehensive documentation is crucial in GLP compliance. Key documentation elements include:
• Study protocols
• Standard operating procedures (SOPs)
• Raw data records
• Analytical reports
• Audit reports
• Equipment calibration records
• Archiving and retention policies
Proper documentation ensures traceability, accountability, and reliability in laboratory research.
Audit in GLP Compliance
Auditing is a critical component of GLP, ensuring adherence to established regulations and identifying areas for improvement. Audits can be internal (self-audit) or external (regulatory or third-party audits).
Goals of Laboratory Quality Audit
• Ensure compliance with GLP regulations.
• Identify gaps and areas for improvement.
• Validate data integrity and accuracy.
• Enhance operational efficiency.
• Prevent regulatory penalties and study disqualification.
Audit Tools in GLP
Laboratories use various audit tools to assess compliance, including:
• Checklists and self-assessments
• Internal quality audits
• Electronic data tracking systems
• Third-party inspections
• Root cause analysis
• Corrective and preventive action (CAPA) plans
Future of GLP Regulations
Learning Objectives:
1. Explain the basis of Nernst potential and its importance in generation of resting membrane potential
2. Comprehend different mechanisms responsible for the genesis of membrane potential
3. Use the Goldman equation to explain how the relative permeability of the ions create a resting membrane potential
Co-Chairs and Presenters, Professor Carel le Roux, MBChB, FRCP, FRCPath, PhD, and Donna H. Ryan, MD, FTOS, discuss obesity in this CME activity titled “Adopting Modern Management Strategies for Obesity: Treating the Patient, Not the Disease.” For the full presentation, downloadable Practice Aids, and complete CME information, and to apply for credit, please visit us at https://bit.ly/40HfQWa. CME credit will be available until March 27, 2026.
### **Acyclovir and Anti-Herpes Medications**
**Acyclovir** is an antiviral medication used to treat infections caused by herpes viruses, including:
- **Herpes simplex virus (HSV-1 & HSV-2)** – Causes cold sores and genital herpes.
- **Varicella-zoster virus (VZV)** – Causes chickenpox and shingles.
### **Mechanism of Action:**
Acyclovir works by inhibiting viral DNA replication. It is activated inside virus-infected cells, where it blocks viral enzymes, preventing the virus from multiplying.
### **Forms & Dosage:**
- **Oral (Tablets/Capsules/Liquid)** – Used for mild to moderate infections.
- **Topical (Cream/Ointment)** – For cold sores and mild skin infections.
- **Intravenous (IV)** – For severe infections like herpes encephalitis.
### **Other Anti-Herpes Medications:**
- **Valacyclovir (Valtrex)** – A prodrug of acyclovir with better absorption.
- **Famciclovir (Famvir)** – Another antiviral with a longer duration of action.
- **Penciclovir (Denavir)** – Used topically for herpes labialis (cold sores).
### **Uses:**
- Treats and manages outbreaks of herpes simplex.
- Reduces the severity and duration of symptoms.
- Used for long-term suppression to prevent recurrent infections.
- Helps in managing shingles and chickenpox.
### **Side Effects:**
- Nausea, vomiting, diarrhea.
- Headache, dizziness, fatigue.
- Rare: Kidney issues, allergic reactions.
### **Precautions:**
- Drink plenty of fluids to prevent kidney issues.
- Not a cure, but helps manage symptoms.
- Safe for most patients but should be used cautiously in people with kidney disease or weakened immune systems.
Plasma and Red Blood Cells - Copy - Copy_AntiCopy.pdfMedicoseAcademics
Delve deep into the intricate world of blood physiology with “Plasma and Red Blood Cells,” a comprehensive lecture presented by Dr. Faiza, Assistant Professor of Physiology. This presentation is meticulously designed for students, educators, and healthcare professionals to enhance their understanding of hematology and the critical roles played by various blood components.
In this lecture, you will:
Examine Blood Composition:
Learn how blood constitutes approximately 8% of total body weight, with precise volumes differing between genders. The presentation breaks down blood into its two fundamental components—plasma and blood cells—and explains their distribution and essential functions in the body.
Understand Plasma Functions and Composition:
Discover the key role of plasma as a transport medium for nutrients, waste products, hormones, and ions. The lecture details the high water content (~90%), the balance of inorganic (e.g., Na⁺, Cl⁻, HCO₃⁻, K⁺, Ca²⁺) and organic substances (notably plasma proteins), and how these components contribute to maintaining homeostasis, temperature regulation, and pH balance.
Classify Plasma Proteins:
Explore the classification of plasma proteins into albumins, globulins (alpha, beta, and gamma), and fibrinogen. Learn about their individual functions, such as maintaining colloid osmotic pressure, facilitating transport of poorly soluble substances, and contributing to immune defense and clotting processes.
Analyze Hematocrit and Packed Cell Volume (PCV):
Understand the significance of hematocrit or PCV as a measure of the proportion of erythrocytes in blood, including the average values observed in men and women. This metric is crucial for assessing blood viscosity and overall health.
Study the Structure and Function of Erythrocytes:
Gain insight into the unique characteristics of red blood cells, including their biconcave disc shape, deformability, and the absence of organelles, which all play a role in optimizing oxygen transport. Detailed discussions cover the enzymes involved in RBC metabolism and the physiological basis for their limited lifespan.
Relate to Clinical and Physiological Contexts:
The lecture also connects these fundamental concepts to clinical scenarios, explaining how alterations in blood composition can impact oxygen delivery, acid-base balance, and overall metabolic function. It provides a solid foundation for understanding common hematological disorders and the body’s adaptive mechanisms in various pathological conditions.
Each slide is carefully structured to build a comprehensive picture of blood components and their interplay, supported by visual aids such as flow diagrams, comparative charts, and schematic representations. Dr. Faiza’s expertise is evident as she translates complex physiological processes into accessible and practical knowledge, making this presentation a valuable resource for enhancing your medical education.
CROUP.pdf FOR NURSING STUDENTS CREATED BY KIRAN KARETHAKIRAN KARETHA
Croup is a common childhood illness characterized by swelling
in the airway (larynx, Trachea and bronchi), leading to a
distinctive barking cough and difficulty in breathing, often with
a high-pitched, noisy sound called stridor when inhaling.
It is also known as laryngotracheobronchitis.
THE WESTLEY SCORE: classification of croup severity
SCORING SYSTEM:
A total score of < 2 indicates mild croup.
A total score of 3-5 is classifies as moderate croup.
A total score of 6-11 indicates severe croup.
A total score of >12 indicates impending respiratory failure.
The score ranges from 0-17.
MANAGEMENT:
Supportive care including intravenous fluids to maintain hydration
and oxygen inhalation to relieve hypoxia has to be given.
A single dose of dexamethasone 0.6mg/kg may decrease severity
and duration of illness.
Inhalation of epinephrine may decrease the symptoms of stridor and
respiratory distress immediately.
PREVENTION:
Many cases of croup have been prevented by immunization for
influenza and diphtheria.
Learning Objectives:
1. Discuss free water clearance
2. Differentiate between diabetes insipidus and SIADH
3. Describe the control of extracellular fluid osmolarity and sodium concentration in terms of the osmoreceptor-ADH system and thirst mechanism
4. Describe the roles of Angiotensin II, Aldosterone, and salt appetite mechanism in the control of extracellular fluid osmolarity and sodium concentration
Yasser’s Electrocardiographic Palpitations Wave with Bilobed Apical Floating ...YasserMohammedHassan1
Bilobed Apex heart with Floating Heart syndrome is an innovative cardiovascular and radiological discovery. The Bilobed Apex heart with Floating Heart syndrome with "Yasser’s Electrocardiographic Palpitations Waves" and off-phenomenon post-amiodarone IVB injection are remarkable innovative constellations. "Yasser’s Electrocardiographic Palpitations Waves" was shortly described as a superficial upright wave associated with unusual palpitations. Bilobed Apex heart with Floating Heart has no known cause. It is mostly congenital. The senses of sudden heart stoppage, generalized fatigue, vertigo, acute confusion, generalized body relaxation, a sense of separation from the environment, and a sense of no abnormality within minutes of amiodarone IVB injection are an off phenomenon.
Artificial Intelligence in Medical Studies.pptxMahnoor Fatima
This presentation explores the integration of Artificial Intelligence (AI) in medical studies, focusing on its benefits, challenges, and ethical considerations. As AI continues to shape modern healthcare, understanding students’ perspectives is crucial in designing future medical education programs.
Growth and development milestone 7 months .pptxAbhishek Verma
Growth and developed milestone for a 7 months old children
Milestone 7 months
At seven months, your baby is becoming more active, curious, and expressive! Many can sit up without support, reach for toys, and even start rocking on their hands and knees, a sign that crawling is coming soon. Their grip is improving, so they enjoy grabbing, shaking, and banging objects together.
Socially, they recognize their name, respond to familiar voices, and may show separation anxiety when a parent leaves the room. They love interactive games like peekaboo and enjoy babbling sounds like “ba-ba” and “da-da.”
Solid foods are now a regular part of their diet, along with breast milk or formula. They may sleep 12–16 hours a day, including two or three naps.
Every baby develops at their own pace, so don’t worry if they’re not hitting every milestone at the same time as others. Enjoy this exciting stage of discovery and growth.
Discover the essential growth and development milestones of a 7-month-old baby. Learn about physical, cognitive, emotional, and social developments, including motor skills, sensory awareness, speech progress, and feeding habits. Get expert parenting tips, activities, and guidance to support your baby's healthy development. Stay informed with this comprehensive guide
Wondering what milestones your 7-month-old should be reaching? This expert guide covers key physical, cognitive, and social developments, from sitting up and babbling to improved
hand-eye coordination. Learn about feeding,
sleep patterns, and fun activities to support your baby's growth. Get top parenting tips and insights to ensure your little one thrives!
#pediatricnursing #Growthanddevelopment
#Growthanddevelopmentalmilestones
Growth and development ppt
Growth and development milestone slideshare ppt
"Comprehensive Medical Guide - Health & Medicine Insights (v10.a5.01)"Victoria855690
"This document provides valuable insights into health and medicine, covering essential topics such as medical research, healthcare practices, disease management, and treatment approaches. It is useful for students, professionals, and researchers in the medical field. The content is well-structured, making complex medical concepts easier to understand."
Prescribing for Heart Failure: A Guide for MBBS StudentsShivankan Kakkar
This SlideShare presentation provides a concise reference for MBBS students on prescription writing for heart failure. It covers key medications, treatment approaches, and clinical guidelines for effective management.
Approach to anemia , classification, investigations casesFatimahRaad
Pdf simply about how to reach to anemia diagnosis with presenting signs and symptoms mainly based on investigations we send in this file as well as discuss two case scenarios on this common health problem from reference book core clinical cases medicine and medical specialties
TRACHEOESOPHAGEAL FISTULA.pdf FOR NURSING STUDENTSKIRAN KARETHA
Tracheoesophageal fistula is an abnormal connection between the
trachea and esophagus.
It occurs in 1 in 3,500 births
Type A (esophageal atresia)
Type B (esophageal atresia with proximal fistula)
Type C (esophageal atresia with Distal fistula)
Type D (esophageal atresia with proximal and distal fistula)
Type E (H- typed fistula)
AI Trends in Creative Operations 2024 by Artwork Flow.pdfmarketingartwork
Creative operations teams expect increased AI use in 2024. Currently, over half of tasks are not AI-enabled, but this is expected to decrease in the coming year. ChatGPT is the most popular AI tool currently. Business leaders are more actively exploring AI benefits than individual contributors. Most respondents do not believe AI will impact workforce size in 2024. However, some inhibitions still exist around AI accuracy and lack of understanding. Creatives primarily want to use AI to save time on mundane tasks and boost productivity.
Organizational culture includes values, norms, systems, symbols, language, assumptions, beliefs, and habits that influence employee behaviors and how people interpret those behaviors. It is important because culture can help or hinder a company's success. Some key aspects of Netflix's culture that help it achieve results include hiring smartly so every position has stars, focusing on attitude over just aptitude, and having a strict policy against peacocks, whiners, and jerks.
PEPSICO Presentation to CAGNY Conference Feb 2024Neil Kimberley
PepsiCo provided a safe harbor statement noting that any forward-looking statements are based on currently available information and are subject to risks and uncertainties. It also provided information on non-GAAP measures and directing readers to its website for disclosure and reconciliation. The document then discussed PepsiCo's business overview, including that it is a global beverage and convenient food company with iconic brands, $91 billion in net revenue in 2023, and nearly $14 billion in core operating profit. It operates through a divisional structure with a focus on local consumers.
Content Methodology: A Best Practices Report (Webinar)contently
This document provides an overview of content methodology best practices. It defines content methodology as establishing objectives, KPIs, and a culture of continuous learning and iteration. An effective methodology focuses on connecting with audiences, creating optimal content, and optimizing processes. It also discusses why a methodology is needed due to the competitive landscape, proliferation of channels, and opportunities for improvement. Components of an effective methodology include defining objectives and KPIs, audience analysis, identifying opportunities, and evaluating resources. The document concludes with recommendations around creating a content plan, testing and optimizing content over 90 days.
How to Prepare For a Successful Job Search for 2024Albert Qian
The document provides guidance on preparing a job search for 2024. It discusses the state of the job market, focusing on growth in AI and healthcare but also continued layoffs. It recommends figuring out what you want to do by researching interests and skills, then conducting informational interviews. The job search should involve building a personal brand on LinkedIn, actively applying to jobs, tailoring resumes and interviews, maintaining job hunting as a habit, and continuing self-improvement. Once hired, the document advises setting new goals and keeping skills and networking active in case of future opportunities.
A report by thenetworkone and Kurio.
The contributing experts and agencies are (in an alphabetical order): Sylwia Rytel, Social Media Supervisor, 180heartbeats + JUNG v MATT (PL), Sharlene Jenner, Vice President - Director of Engagement Strategy, Abelson Taylor (USA), Alex Casanovas, Digital Director, Atrevia (ES), Dora Beilin, Senior Social Strategist, Barrett Hoffher (USA), Min Seo, Campaign Director, Brand New Agency (KR), Deshé M. Gully, Associate Strategist, Day One Agency (USA), Francesca Trevisan, Strategist, Different (IT), Trevor Crossman, CX and Digital Transformation Director; Olivia Hussey, Strategic Planner; Simi Srinarula, Social Media Manager, The Hallway (AUS), James Hebbert, Managing Director, Hylink (CN / UK), Mundy Álvarez, Planning Director; Pedro Rojas, Social Media Manager; Pancho González, CCO, Inbrax (CH), Oana Oprea, Head of Digital Planning, Jam Session Agency (RO), Amy Bottrill, Social Account Director, Launch (UK), Gaby Arriaga, Founder, Leonardo1452 (MX), Shantesh S Row, Creative Director, Liwa (UAE), Rajesh Mehta, Chief Strategy Officer; Dhruv Gaur, Digital Planning Lead; Leonie Mergulhao, Account Supervisor - Social Media & PR, Medulla (IN), Aurelija Plioplytė, Head of Digital & Social, Not Perfect (LI), Daiana Khaidargaliyeva, Account Manager, Osaka Labs (UK / USA), Stefanie Söhnchen, Vice President Digital, PIABO Communications (DE), Elisabeth Winiartati, Managing Consultant, Head of Global Integrated Communications; Lydia Aprina, Account Manager, Integrated Marketing and Communications; Nita Prabowo, Account Manager, Integrated Marketing and Communications; Okhi, Web Developer, PNTR Group (ID), Kei Obusan, Insights Director; Daffi Ranandi, Insights Manager, Radarr (SG), Gautam Reghunath, Co-founder & CEO, Talented (IN), Donagh Humphreys, Head of Social and Digital Innovation, THINKHOUSE (IRE), Sarah Yim, Strategy Director, Zulu Alpha Kilo (CA).
Trends In Paid Search: Navigating The Digital Landscape In 2024Search Engine Journal
The search marketing landscape is evolving rapidly with new technologies, and professionals, like you, rely on innovative paid search strategies to meet changing demands.
It’s important that you’re ready to implement new strategies in 2024.
Check this out and learn the top trends in paid search advertising that are expected to gain traction, so you can drive higher ROI more efficiently in 2024.
You’ll learn:
- The latest trends in AI and automation, and what this means for an evolving paid search ecosystem.
- New developments in privacy and data regulation.
- Emerging ad formats that are expected to make an impact next year.
Watch Sreekant Lanka from iQuanti and Irina Klein from OneMain Financial as they dive into the future of paid search and explore the trends, strategies, and technologies that will shape the search marketing landscape.
If you’re looking to assess your paid search strategy and design an industry-aligned plan for 2024, then this webinar is for you.
5 Public speaking tips from TED - Visualized summarySpeakerHub
From their humble beginnings in 1984, TED has grown into the world’s most powerful amplifier for speakers and thought-leaders to share their ideas. They have over 2,400 filmed talks (not including the 30,000+ TEDx videos) freely available online, and have hosted over 17,500 events around the world.
With over one billion views in a year, it’s no wonder that so many speakers are looking to TED for ideas on how to share their message more effectively.
The article “5 Public-Speaking Tips TED Gives Its Speakers”, by Carmine Gallo for Forbes, gives speakers five practical ways to connect with their audience, and effectively share their ideas on stage.
Whether you are gearing up to get on a TED stage yourself, or just want to master the skills that so many of their speakers possess, these tips and quotes from Chris Anderson, the TED Talks Curator, will encourage you to make the most impactful impression on your audience.
See the full article and more summaries like this on SpeakerHub here: https://speakerhub.com/blog/5-presentation-tips-ted-gives-its-speakers
See the original article on Forbes here:
http://www.forbes.com/forbes/welcome/?toURL=http://www.forbes.com/sites/carminegallo/2016/05/06/5-public-speaking-tips-ted-gives-its-speakers/&refURL=&referrer=#5c07a8221d9b
ChatGPT and the Future of Work - Clark Boyd Clark Boyd
Everyone is in agreement that ChatGPT (and other generative AI tools) will shape the future of work. Yet there is little consensus on exactly how, when, and to what extent this technology will change our world.
Businesses that extract maximum value from ChatGPT will use it as a collaborative tool for everything from brainstorming to technical maintenance.
For individuals, now is the time to pinpoint the skills the future professional will need to thrive in the AI age.
Check out this presentation to understand what ChatGPT is, how it will shape the future of work, and how you can prepare to take advantage.
The document provides career advice for getting into the tech field, including:
- Doing projects and internships in college to build a portfolio.
- Learning about different roles and technologies through industry research.
- Contributing to open source projects to build experience and network.
- Developing a personal brand through a website and social media presence.
- Networking through events, communities, and finding a mentor.
- Practicing interviews through mock interviews and whiteboarding coding questions.
Google's Just Not That Into You: Understanding Core Updates & Search IntentLily Ray
1. Core updates from Google periodically change how its algorithms assess and rank websites and pages. This can impact rankings through shifts in user intent, site quality issues being caught up to, world events influencing queries, and overhauls to search like the E-A-T framework.
2. There are many possible user intents beyond just transactional, navigational and informational. Identifying intent shifts is important during core updates. Sites may need to optimize for new intents through different content types and sections.
3. Responding effectively to core updates requires analyzing "before and after" data to understand changes, identifying new intents or page types, and ensuring content matches appropriate intents across video, images, knowledge graphs and more.
A brief introduction to DataScience with explaining of the concepts, algorithms, machine learning, supervised and unsupervised learning, clustering, statistics, data preprocessing, real-world applications etc.
It's part of a Data Science Corner Campaign where I will be discussing the fundamentals of DataScience, AIML, Statistics etc.
Time Management & Productivity - Best PracticesVit Horky
Here's my presentation on by proven best practices how to manage your work time effectively and how to improve your productivity. It includes practical tips and how to use tools such as Slack, Google Apps, Hubspot, Google Calendar, Gmail and others.
The six step guide to practical project managementMindGenius
The six step guide to practical project management
If you think managing projects is too difficult, think again.
We’ve stripped back project management processes to the
basics – to make it quicker and easier, without sacrificing
the vital ingredients for success.
“If you’re looking for some real-world guidance, then The Six Step Guide to Practical Project Management will help.”
Dr Andrew Makar, Tactical Project Management
Unlocking the Power of ChatGPT and AI in Testing - A Real-World Look, present...Applitools
During this webinar, Anand Bagmar demonstrates how AI tools such as ChatGPT can be applied to various stages of the software development life cycle (SDLC) using an eCommerce application case study. Find the on-demand recording and more info at https://applitools.info/b59
Key takeaways:
• Learn how to use ChatGPT to add AI power to your testing and test automation
• Understand the limitations of the technology and where human expertise is crucial
• Gain insight into different AI-based tools
• Adopt AI-based tools to stay relevant and optimize work for developers and testers
* ChatGPT and OpenAI belong to OpenAI, L.L.C.
The document discusses various AI tools from OpenAI like GPT-3 and DALL-E 2, as well as ChatGPT. It explores how search engines are using AI and things to consider around AI-generated content. Potential SEO uses of ChatGPT are also presented, such as generating content at scale, conducting topic research, and automating basic coding tasks. The document encourages further reading on using ChatGPT for SEO purposes.
More than Just Lines on a Map: Best Practices for U.S Bike Routes
This session highlights best practices and lessons learned for U.S. Bike Route System designation, as well as how and why these routes should be integrated into bicycle planning at the local and regional level.
Presenters:
Presenter: Kevin Luecke Toole Design Group
Co-Presenter: Virginia Sullivan Adventure Cycling Association
Asmr what is it and why did this type of video go viral on the internet
1. ASMR | What is it and why did this type of
video go viral on the internet?
After a stressful day what do you do to relax? If the answer is to leave the front of the
computer screen (or cell phone), it's time to review your concepts.
This is because the solution to problems such as stress, anxiety and even insomnia can be
exactly on the internet, more precisely on YouTube, in the acclaimed ASMR videos.
But what is ASMR? These videos are becoming increasingly popular. On YouTube, there are
already specialized channels in the production of this type of "content".
Meanwhile, on Twitch, a specific category brings together streamers doing live broadcasts of
ASMR.
ALL ASMR VIDEOS FOR YOUR REST AND RELAXATION (FREE) - https://oke.io/jU1TCN
But what is ASMR?
The acronym for Autonomous Sensory Meridian Response is nothing more than an
autonomous southern sensory response, that is, a pleasant sensation generated in the body
by an external stimulus, which in ASMR videos is usually audible or visual.
Think of sequences that can reach 60 minutes of people popping a piece of bubble wrap,
making a meal, talking softly or cutting bars of colored soap.
Currently, it is estimated that, on YouTube alone, millions of people watch ASMR productions
every day in search of relaxation, increased concentration or a better night's sleep.
ASMR and YouTube
Sometimes, staying connected on your cell phone takes our sleep away. Talking to friends
and watching news updates feels better than sleeping and makes us stay up more hours.
Difficulty turning off is a problem that has several levels and can cause insomnia.
Some people search for the solution exactly on the internet and there are YouTubers
recording videos and making use of ASMR, which promises to be the secret for those who
want to concentrate, disconnect and sleep more easily.
2. To generate more concentration, most of these productions fit only the person's face or,
sometimes, just the mouth.
These "instructors" also often make gestures towards the camera to explore the feeling of
physical and even affective contact. There are reports that, in addition to drowsiness and
concentration, these videos give a tingling sensation to those who watch.
Even without scientific evidence, Autonomous Sensory Meridian Response (ASMR) has
been making the heads of many people. Or rather, the ears.
And it has become a lucrative business for youtubers, meditation and relaxation apps.
Understand better how these sounds, almost whispered, “hypnotize” listeners (or, at least,
promise this) on our Youtube channel - ASMR SLEEP - Relaxing Music.
ALL ASMR VIDEOS FOR YOUR REST AND RELAXATION (FREE) - https://oke.io/jU1TCN
Tingling sensation
Among the ASMR effects, fans describe a tingling sensation. It was reported by 88% of
respondents to British research at Swansea University.
Camila describes this as a shiver that goes from the nape of the neck to the top of the head.
"The more you feel, it seems that it is inducing sleep, and brings a great feeling of
well-being", explains the student.
This tingling can originate in only one part of the body or vary in location. Most respondents
to the British survey reported that the tingles would originate behind the head, shoulders,
spine, arms and legs.
Benefits of ASMR
The data is part of a study by Swansea University in the UK, which questioned 475 people
who watched videos of ASMR about the benefits experienced with the practice.
● Relaxation (98%)
● Promotion of sleep (82%)
● Decreased stress (70%)
Only 5% agreed that they felt some sexual stimulation with the videos. Among those who
had chronic pain, 38% noticed improvement after joining the ASMR videos.
3. Types of ASMR content
The magic of ASMR is the trigger that will awaken the pleasurable sensations in those who
watch the videos. A Swansea University survey on the topic ranked a favorite ranking:
1. Whispers (75%)
2. Personal attention (69%)
3. Clear sounds (biting nails, scratching, etc.) (64%)
4. Slow sounds (53%)
5. Sounds repetitive (36%)
6. smile (13%)
7. airplane noise (3%)
8. vacuum cleaner noise (2%)
9. laughter (2%)
Another technique of ASMR videos is the reproduction of sounds that simulate everyday
situations that involuntarily end up having a relaxing effect on the viewer. They are called
"roleplays".
How to explain the ASMR phenomenon?
With so much demand, it is inevitable to try to understand the popularity of content as unusual
as ASMR. And perhaps the answer to what "ASMR" is lies in science.
There is still little research on the subject, but a study by the Department of Psychology at the
University of Sheffield, England, monitored the reactions of volunteers when watching
ordinary and ASMR videos.
The conclusion was that people who watched the ASMR content had their heart rates
significantly reduced and were still more relaxed and more likely to have positive thoughts.
These characteristics are similar to the sensations caused by other scientifically proven stress
reduction techniques, such as listening to music or even mindfulness, the state of mindfulness
in the present.
Although sensations such as tingling and pleasure reported by ASMR viewers are evidence
that points to the benefits reported by those who frequently watch videos, what is known in
fact is that much of this is due to the distraction factor they cause and also to the sensitivity
each one.